Endocrine Abstracts

Introduction: Acromegaly is a rare disease of the pituitary gland. Both GH and IGF-1 levels are of key importance for monitoring of treatment effects in patients with acromegaly. In some patients, divergent results of measurements of these hormones are observed. Purpose: The purpose of the study was to estimate frequency of GH and IGF-1 inconsistencies in the population of patients with acromegaly included in the Polish Register of Acromegaly Patients, a...

Hypoparathyroidism following parathyroidectomy is commonly treated with activated vitamin D, (alfacalcidol and calcitriol). Alfacalcidol (1-hydroxyvitamin D) is converted by hepatic 25-hydroxylase to generate calcitriol (1,25-dihydroxyvitamin D) to act on target cells.We present the case of 66 year old man who was admitted with chest pain in November 2016 and found to have corrected calcium of 1.5 mmol/litre and PO4 2.7 mmol/litre....

Hypoparathyroidism following parathyroidectomy is commonly treated with activated vitamin D, (alfacalcidol and calcitriol). Alfacalcidol (1-hydroxyvitamin D) is converted by hepatic 25-hydroxylase to generate calcitriol (1,25-dihydroxyvitamin D) to act on target cells.We present the case of 66 year old man who was admitted with chest pain in November 2016 and found to have corrected calcium of 1.5 mmol/litre and PO4 2.7 mmol/litre....

Introduction: False memory, that is, remembering events, prohibitions and recommendations that did not happen. This phenomenon has long been known in forensics as it seems to be much more recognized in everyday life. This also applies to patients who could significantly interfere with communication with the doctor and education opportunities. In the face of surprisingly few papers on this subject regarding diabetes, we would like to present our observation.<p class="abstex...

Acromegaly is a rare endocrine disorder caused by growth hormone (GH) secreting pituitary adenoma. The treatment of choice is transsphenoidal surgery. In patients with persistent disease after surgery medical therapy is recommended. First-line medical treatment include first generation long-acting somatostatin analogs: octreotide LAR and lanreotide autogel. Recently, pasireotide – a second generation somatostatin analog has been investigated in patients with acromegaly.</...

Introduction: The phenomenon of false memory is quite prevalent among people with cognitive impairment. Cognitive dysfunction and its relationship with the thyroid gland has been described. In contrast, little is known about the phenomenon of false memory in patients with thyroid diseases. That is why we want to introduce our preliminary observation.Method: Patients aged 64 to 90 years (average 77) with endocrine disorders were subjected to tests for typ...

Aim: The aim of this study was to evaluate hormonal disturbances and adipokines levels in girls with oligomenorrhea.Materials and methods: The study comprised a group of 46 girls, aged 16–18 years, who were diagnosed with oligomenorrhea, and a control group with 37 healthy girls, aged 16–18 years, with no diagnosed menstrual disorders. In the first stage of the study, all girls had their medical history assessed. Subsequently, anthropometric me...

Introduction: Fine needle aspiration biopsy (FNAB) plays a crucial role in the diagnosis of thyroid nodules. The choice of further therapeutic strategy depends largely on its result. Knowledge of the risk of malignancy in each diagnosis class in the population is necessary. The aim of the research was to analyse the risk of malignancy in thyroid nodules in each diagnosis class according to Bethesda system.Materials and methods: Retrospective research inc...

Introduction: Over expression of somatostatin receptors (SSTR) is the characteristic feature of well differentiated neuroendocrine neoplasms (NENs). We present two patients with well differentiated NENs of the large intestine with negative SRS and without SSTR expression confirmed with immunohistochemical (IHCH) examination and symptoms of carcinoid syndrome with good clinical response to the therapy with long acting somatostatin analogs.Case reports: 53...

Introduction: Prader–Willi syndrome (PWS) is a genetic syndrome usually diagnosed in childhood. Its reported prevalence ranges from one in 8000 to one in 45 000 with geographical variation. Clinical manifestations include obesity, hyperphagia, short stature, incomplete sexual development, and cognitive disabilities. The majority of published data regarding PWS comes from paediatric populations.Materials and methods: This is a retrospective observati...